Hi @RussellAshton ,
Have you ensured that you're calculating LODs in the DRS? And if so, can you see them in the Results View - Data Table? You can turn them on/off using the options button at the top.
If you're still getting zeroes, you could check that this is not because you have no variation in your background values by also calculating the Howell et al and Pettke et al LODs (the latter requires dwell time info for each channel though).
Please let us know how you go.